Browsing by Author "Kaplan, Oktay I."
Now showing items 1-5 of 5
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ARL13B regulates juxtaposed cilia-cilia elongation in BBSome dependent manner in Caenorhabditis elegans
Turan, Merve Gul; Kantarci, Hanife; Cevik, Sebiha; Kaplan, Oktay I. (CELL PRESS, 2025)The interaction of cilia with various cellular compartments, such as axons, has emerged as a new form of cellular communication. Cilia often extend in proximity to cilia from neighboring cells. However, the mechanisms ... -
The Joubert syndrome protein CEP41 is excluded from the distal segment of cilia in C. elegans
Sebiha Cevik; Oktay I Kaplan (2021)Rare diseases are a fundamental issue in today's world, affecting more than 300 million individuals worldwide. According to data from Orphanet and OMIM, about 50-60 new conditions are added to the list of over 6,000 ... -
MSABrowser: dynamic and fast visualization of sequence alignments, variations and annotations
Torun, Furkan M.; Bilgin, Halil İbrahim; Kaplan, Oktay I. (Oxford University Press, 2021)Sequence alignment is an excellent way to visualize the similarities and differences between DNA, RNA or protein sequences, yet it is currently difficult to jointly view sequence alignment data with genetic variations, ... -
Protocol for determining the average speed and frequency of kinesin and dynein-driven intraflagellar transport (IFT) in C. elegans
Turan, Merve G.; Kantarci, Hanife; Temtek, Sadiye D.; Cakici, Onur; Cevik, Sebiha; Kaplan, Oktay I. (Cell Press, 2022)Here, we present a protocol to image a fluorescent-labeled intraflagellar transport (IFT) component in Caenorhabditis elegans with fluorescence microscopy, including steps of sample preparations, in vivo live-cell imaging, ... -
Subcellular localization of the voltage-gated K+ channel EGL-36 , a member of the KV3 subfamily, in the ciliated sensory neurons in C. elegans
Sebiha Cevik; Oktay I Kaplan (2021)Delineated as the first cellular organelle in 1675 by Antonie van Leeuwenhoek, cilia did not receive much attention until the 2000s, when it became apparent that cilia played a key role in the development of embryos, a ...
