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An integrative-omics analysis of an industrial clavulanic acid-overproducing Streptomyces clavuligerus
Kurt Kızıldoğan, Aslıhan; Çelik, Gözde; Ünsaldı, Eser; Özcan, Servet; Ayaz-Guner, Serife; Özcengiz, Gülay (Springer, 2022)Clavulanic acid (CA) is a clinically important secondary metabolite used to treat infectious diseases. We aimed to decipher complex regulatory mechanisms acting in CA biosynthesis by analyzing transcriptome- and proteome-wide ...