Kurum Yazarı "Akcok, Ismail" İçin Listeleme
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Determination of promising inhibitors for N-SH2 domain of SHP2 tyrosine phosphatase: an in silico study
Akcok, Emel Basak Gencer; Guner, Huseyin; Akcok, Ismail (SPRINGER NATURE LINK, 2024)There are many genes that produce proteins related to diseases and these proteins can be targeted with drugs as a potential therapeutic approach. Recent advancement in drug discovery techniques have created new opportunities ... -
Ethacrynic acid and cinnamic acid combination exhibits selective anticancer effects on K562 chronic myeloid leukemia cells
Yenigul, Munevver; Akcok, Ismail; Gencer Akcok, Emel Basak (SPRINGER, 2022)Background Despite the recent advances in chemotherapy, the outcomes and the success of these treatments still remain insufficient. Novel combination treatments and treatment strategies need to be developed in order to ... -
Rapamycin and Niacin combination induces apoptosis and cell cycle arrest through autophagy activation on acute myeloid leukemia cells
Subay, Lale Beril; Akcok, Emel Basak Gencer; Akcok, Ismail (SPRINGER NATURE LINK, 2025)BackgroundAcute myeloid leukemia (AML) is a heterogeneous hematological malignancy caused by disorders in stem cell differentiation and excessive proliferation resulting in clonal expansion of dysfunctional cells called ...
