Browsing by Author "Icoz, Kutay"
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Ball Lens Based Mobile Microscope
Icoz, Kutay (GAZI UNIVCENTER CAMPUS TECHNOLOGY FAC B BLOCK EK BINA, 2ND FL, ANKARA, 06500, TURKEY, 2016)In this paper we report a low cost, simple and mobile microscope based on attachment of a ball lens to a cell phone. The system's noise and parameters affecting the image quality is investigated. The ball lens provides ... -
Capturing B type acute lymphoblastic leukemia cells using two types of antibodies
Icoz, Kutay; Gercek, Tayyibe; Murat, Aysegul; Ozcan, Servet; Unal, Ekrem (WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2019)One way to monitor minimal residual disease (MRD) is to screen cells for multiple surface markers using flow cytometry. In order to develop an alternative microfluidic based method, isolation of B type acute lymphoblastic ... -
Deep learning based semantic segmentation and quantification for MRD biochip images
Çelebi, Fatma; Tasdemir, Kasim; Icoz, Kutay (ELSEVIER SCI LTD, 2022)Microfluidic platforms offer prominent advantages for the early detection of cancer and monitoring the patient response to therapy. Numerous microfluidic platforms have been developed for capturing and quantifying the tumor ... -
Design, modeling, and control of a horizontal magnetic micromanipulator
Ablay, Gunyaz; Boyuk, Mustafa; Icoz, Kutay (SAGE PUBLICATIONS LTD, 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND, 2019)Magnetic micromanipulators with a wide range of force generating capabilities are able to manipulate micron size particles for various applications and measurements. These magnetic particles can be coated with receptors ... -
Detection of Proteins Using Nano Magnetic Particle Accumulation-Based Signal Amplification
Icoz, Kutay; Mzava, Omary (MDPI, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2016)We report a biosensing method based on magnetic particles where coated magnetic particles are used for immunomagnetic separation, and uncoated magnetic particles are used for signal enhancement. To quantify the signal ... -
Feedback controller designs for an electromagnetic micromanipulator
Boyuk, Mustafa; Eroglu, Yakup; Ablay, Gunyaz; Icoz, Kutay (SAGE PUBLICATIONS LTD, 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND, 2019)Magnetic micromanipulators are capable of generating wide range of magnetic forces to manipulate magnetic microparticles for biomedical applications. In this study, a multipole magnetic micromanipulator system including ... -
High spatial resolution IoT based air PM measurement system
Icoz, Ebru; Malik, Fasih M.; Icoz, Kutay (SPRINGERVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, 2021)Air pollution is one of the global problems of the current era. According to World Health Organization more than 80% of the people living in metropolitan areas breathe air which exceeds the guideline limits. Particulate ... -
A horizontal magnetic tweezer for single molecule micromanipulations
Ablay, Gunyaz; Boyuk, Mustafa; Eroglu, Yakup; Icoz, Kutay (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)Magnetic tweezers are able to manipulate cells or biomolecules for various applications and measurements. In this work, a horizontal magnetic tweezer is designed, modeled and controlled for single molecule manipulations. ... -
Image Processing and Cell Phone Microscopy to Analyze the Immunomagnetic Beads on Micro-Contact Printed Gratings
Icoz, Kutay (MDPI AG, ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2016)In this paper we report an ultra-low-cost spherical ball lens based cell phone microscopy and image processing algorithms to analyze the amount of immunomagnetic beads on micro-contact printed gratings. The spherical ball ... -
Image-analysis based readout method for biochip: Automated quantification of immunomagnetic beads, micropads and patient leukemia cell
Uslu, Fatma; Icoz, Kutay; Tasdemir, Kasim; Dogan, Refika S.; Yilmaz, Bulent (PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2020)For diagnosing and monitoring the progress of cancer, detection and quantification of tumor cells is utmost important. Beside standard bench top instruments, several biochip-based methods have been developed for this ... -
Image-Processing Based Signal Readout Method for MRD Biochip
Uslu, Fatma; Icoz, Kutay; Tasdemir, Kasim (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2019)The response of the cancer patients to chemotherapy treatment varies from person to person. For some patients cancer cells are resistant to treatment and these cells can relapse again which is known as minimal residual ... -
Immunomagnetic separation of B type acute lymphoblastic leukemia cells from bone marrow with flow cytometry validation and microfluidic chip measurements
Icoz, Kutay; Eken, Ahmet; Cinar, Suzan; Murat, Aysegul; Ozcan, Servet; Unal, Ekrem; Deniz, Gunnur (TAYLOR & FRANCIS INC, 530 WALNUT STREET, STE 850, PHILADELPHIA, PA 19106 USA, 2020)In order to detect the blast cells from bone marrow of patients, one strategy is to first isolate the cells using immunomagnetic beads. The aim of this study was to report the experimental results of the immunomagnetic ... -
Improving short-term memory performance of healthy young males using alpha band neurofeedback
Gökşin, Barış; Yılmaz, Bülent; Icoz, Kutay (International Society for Neurofeedback and Research, 2019)To examine whether it was possible to improve short-term memory performance of healthy participants by increasing relative alpha band power (7–11.5 Hz) using neurofeedback, we first converted a commercial EEG device ... -
Magnetic micro/nanoparticle flocculation-based signal amplification for biosensing
Mzava, Omary; Tas, Zehra; Icoz, Kutay (DOVE MEDICAL PRESS LTD, PO BOX 300-008, ALBANY, AUCKLAND 0752, NEW ZEALAND, 07.07.2016)We report a time and cost efficient signal amplification method for biosensors employing magnetic particles. In this method, magnetic particles in an applied external magnetic field form magnetic dipoles, interact with ... -
Magnetic-particle based signal amplification method integrated with mobile-devices for low cost biosensing
Mzava, Omary; Tas, Zehra; Lafci, Vahit Can; Cakar, Mehmet Akif; Ozdur, Ibrahim; Icoz, Kutay (ELSEVIER SCIENCE BV, SARA BURGERHARTSTRAAT 25, PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS, 2017)We present a signal amplification method for biosensing applications using magnetic particles. In this method, mobile devices and simple spherical glass beads are used as a low-cost microscope to detect magnetic particles. ... -
Micro- and nanodevices integrated with biomolecular probes
Alapan, Yunus; Icoz, Kutay; Gurkan, Umut A. (PERGAMON-ELSEVIER SCIENCE LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2015)Understanding how biomolecules, proteins and cells interact with their surroundings and other biological entities has become the fundamental design criterion for most biomedical micro- and nanodevices. Advances in biology, ... -
Microfluidic Chip based direct triple antibody immunoassay for monitoring patient comparative response to leukemia treatment
Icoz, Kutay; Akar, Unal; Unal, Ekrem (SPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, 2020)We report a time and cost-efficient microfluidic chip for screening the leukemia cells having three specific antigens. In this method, the target blast cells are double sorted with immunomagnetic beads and captured by the ... -
On-demand weighing of single dry biological particles over a 5-order-of-magnitude dynamic range
Chan, Bin-Da; Huang, Wanfeng; Chang, Chun-Li; Savran, Cagri A.; Icoz, Kutay (ROYAL SOC CHEMISTRY, 2014)We report a simple and highly versatile system to select and weigh individual dry biological particles. The system is composed of a microtweezer to pick and place individual particles and a cantilever-based resonator to ... -
Optical detection of microplastics in water
Iri, Ahmet H.; Shahrah, Malek H. A.; Ali, Ali M.; Qadri, Sayed A.; Erdem, Talha; Ozdur, Ibrahim T.; Icoz, Kutay (SPRINGER HEIDELBERGTIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY, 2021)Unfortunately, the plastic pollution increases at an exponential rate and drastically endangers the marine ecosystem. According to World Health Organization (WHO), microplastics in drinking water have become a concern and ... -
Parameter investigation of topological data analysis for EEG signals
Altindis, Fatih; Yilmaz, Bulent; Borisenok, Sergey; Icoz, Kutay (ELSEVIER SCI LTD, THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 01.01.2021)Topological data analysis (TDA) methods have become appealing in EEG signal processing, because they may help the scientists explore new features of complex and large amount of data by simplifying the process from a ...
