Yazar "0000-0002-2272-6270" için Bilgisayar Mühendisliği Bölümü Koleksiyonu listeleme
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AMP-GSM: Prediction of Antimicrobial Peptides via a Grouping–Scoring–Modeling Approach
Soylemez, Ummu Gulsum; Yousef, Malik; Bakir-Gungor, Burcu (MDPI, 2023)Due to the increasing resistance of bacteria to antibiotics, scientists began seeking new solutions against this problem. One of the most promising solutions in this field are antimicrobial peptides (AMP). To identify ... -
Blockchain-based Fog Computing Applications in Healthcare
Adanur, Beyhan; Bakir-Gungor, Burcu; Soran, Ahmet (IEEE, 2020)— Son zamanlarda blokzincir teknolojisinin sağlık alanında kullanımı artmıştır. Blokzincir teknolojisinin sağlık alanına getirdiği birçok yenilik olmasına rağmen, halen çözülmeyi bekleyen problemleri mevcuttur. Bu ... -
COMPARATIVE PERFORMANCE ANALYSIS OF ARIMA, PROPHET AND HOLT-WINTERS FORECASTING METHODS ON EUROPEAN COVID-19 DATA
Ersöz, Nur Şebnem; Güner Şahan, Pınar; Akbas, Ayhan; Bakır Güngör, Burcu (Kerim ÇETİNKAYA, 2022)COVID-19 is the most common infectious disease of the last few years and has caused an outbreak all around the world. The mortality rate, which was earlier in the hundreds, increased to thousands and then to millions. ... -
A comparative study on psychiatric disorders: Identification of shared pathways and common agents
Kuzudisli, Cihan; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2022)Distinct but closely related diseases generally present shared symptoms, which address possible overlaps among their pathogenic mechanisms. Identification of significantly impacted shared pathways and other common agents ... -
Developing a label propagation approach for cancer subtype classification problem
Guner, Pinar; Bakir-Gungor, Burcu; Coskun, Mustafa (TUBITAK SCIENTIFIC & TECHNICAL RESEARCH COUNCIL TURKEYATATURK BULVARI NO 221, KAVAKLIDERE, ANKARA 00000, TURKEY, 2022)Cancer is a disease in which abnormal cells grow uncontrollably and invade other tissues. Several types of cancer have various subtypes with different clinical and biological implications. Based on these differences, ... -
The Effect of Different Classifiers on Recursive Cluster Elimination in the Analysis of Transcriptomic Data
Bulut, Nurten; Bakir-Gungor, Burcu; Qaqish, Bahjat F.; Yousef, Malik (Institute of Electrical and Electronics Engineers Inc., 2023)Gene expression data with limited sample size and a large number of genes are frequently encountered in genetic studies. In such high-dimensional data, identification of genes that distinguish between disease states is ... -
Effect of Recursive Cluster Elimination with Different Clustering Algorithms Applied to Gene Expression Data
Kuzudisli, Cihan; Bakir-Gungor, Burcu; Qaqish, Bahjat F.; Yousef, Malik. (Institute of Electrical and Electronics Engineers Inc., 2023)Feature selection (FS) is an effective tool in dealing with high dimensionality and reducing computational cost. Support Vector Machines – Recursive Cluster Elimination (SVM-RCE) is one of several algorithms that have ... -
Enlightening the molecular mechanisms of type 2 diabetes with a novel pathway clustering and pathway subnetwork approach
Bakır Güngör, Burcu; Ünlü, Yazıcı, Miray; Göy, Gökhan; Temiz, Mustafa (TUBITAK, 2022)Type 2 diabetes mellitus (T2D) constitutes 90% of the diabetes cases, and it is a complex multifactorial disease. In the last decade, genome-wide association studies (GWASs) for T2D successfully pinpointed the genetic ... -
Ensemble feature selection and classification methods for machine learning-based coronary artery disease diagnosis
Kolukisa, Burak; Bakir-Gungor, Burcu (ELSEVIER, 2023)Coronary artery disease (CAD) is a condition in which the heart is not fed sufficiently as a result of the accumulation of fatty matter. As reported by the World Health Organization, around 32% of the total deaths in the ... -
An Ensemble Feature Selection Methodology That Incorporates Domain Knowledge for Cardiovascular Disease Diagnosis
Kolukisa, Burak; Güngör, Vehbi Çağrı; Gungor, Burcu Bakir (IEEE, 2020)Koroner Arter Hastalığı (KAH), arterlerin duvarlarında aterom denilen yağlı madde birikiminin bir sonucu olarak kalbin yeterince beslenememesi durumudur. KAH, 2016 yılında dünyadaki toplam ölümlerin %31'ine (17,9 milyon) ... -
Evaluation of Sub-Network search programs in epilepsy-related GWAS dataset
Bakir Gungor, Burcu; Adanur Dedetürk, Beyhan (Pamukkale Üniversitesi, 2022)The active sub-network detection aims to find a group of interconnected genes of disease-related genes in a protein-protein interaction network. In recent years, several algorithms have been developed for this problem. ... -
GeNetOntology: identifying affected gene ontology terms via grouping, scoring, and modeling of gene expression data utilizing biological knowledge-based machine learning
Ersoz, Nur Sebnem; Bakir-Gungor, Burcu; Yousef, Malik (FRONTIERS MEDIA SA, 2023)Introduction: Identifying significant sets of genes that are up/downregulated under specific conditions is vital to understand disease development mechanisms at the molecular level. Along this line, in order to analyze ... -
The Identification of Discriminative Single Nucleotide Polymorphism Sets for the Classification of Behcet's Disease
Gormez, Yasin; Isik, Yunus Emre; Bakir-Gungor, Burcu (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)Behcet's disease is a long-term multisystem inflammatory disorder, characterized by recurrent attacks affecting several organs. As the genotyping individuals get cheaper and easier following the developments in genomic ... -
Identify Commonly Affected Pathways in Psychiatric Diseases
Bulut, Umit; Bakir-Gungor, Burcu (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)Genome-wide association studies (GWAS) are an extraordinary source of information when it comes to revealing the common variations of human complex diseases. Until now, the large amount of data generated from these studies ... -
Identifying Taxonomic Biomarkers of Colorectal Cancer in Human Intestinal Microbiota Using Multiple Feature Selection Methods
Jabeer, Amhar; Kocak, Aysegul; Akkas, Huseyin; Yenisert, Ferhan; Nalbantoglu, Ozkan Ufuk; Yousef, Malik; Bakir Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2022)A variety of bacterial species called gut microbiota work together to maintain a steady intestinal environment. The gastrointestinal tract contains tremendous amount of different species including archaea, bacteria, fungi, ... -
Invention of 3Mint for feature grouping and scoring in multi-omics
Yazici, Miray Unlu; Marron, J. S.; Bakir-Gungor, Burcu; Zou, Fei; Yousef, Malik (FRONTIERS MEDIA SA, 2023)Advanced genomic and molecular profiling technologies accelerated the enlightenment of the regulatory mechanisms behind cancer development and progression, and the targeted therapies in patients. Along this line, intense ... -
Machine Learning Analysis of Inflammatory Bowel Disease-Associated Metagenomics Dataset
Hacilar, Hilal; Nalbantoglu, O. Ufuk; Bakir-Gungor, Burcu (IEEE, 345 E 47TH ST, NEW YORK, NY 10017 USA, 2018)There is an ongoing interplay between humans and our microbial communities. The microorganisms living in our gut produce energy from our food, strengthen our immune system, break down foreign products, and release metabolites ... -
microBiomeGSM: the identification of taxonomic biomarkers from metagenomic data using grouping, scoring and modeling (G-S-M) approach
Bakir-Gungor, Burcu; Temiz, Mustafa; Jabeer, Amhar; Wu, Di; Yousef, Malik (FRONTIERS MEDIA SA, 2023)Numerous biological environments have been characterized with the advent of metagenomic sequencing using next generation sequencing which lays out the relative abundance values of microbial taxa. Modeling the human microbiome ... -
miRcorrNet: machine learning-based integration of miRNA and mRNA expression profiles, combined with feature grouping and ranking
Yousef, Malik; Goy, Gokhan; Mitra, Ramkrishna; Eischen, Christine M.; Jabeer, Amhar; Bakir-Gungor, Burcu (PEERJ INC341-345 OLD ST, THIRD FLR, LONDON EC1V 9LL, ENGLAND, 2021)A better understanding of disease development and progression mechanisms at the molecular level is critical both for the diagnosis of a disease and for the development of therapeutic approaches. The advancements in high ... -
miRcorrNetPro: Unraveling Algorithmic Insights through Cross-Validation in Multi-Omics Integration for Comprehensive Data Analysis
Yazici, Miray Unlu; Yousef, Malik; Marron J.S.; Bakir-Gungor, Burcu (Institute of Electrical and Electronics Engineers Inc., 2023)High throughput -omics technologies facilitate the investigation of regulatory mechanisms of complex diseases. Along this line, scientists develop promising tools and methods to extend our understanding at the molecular ...