Bilgisayar Mühendisliği Bölümü Koleksiyonu by Institution Author "Bakir-Gungor, Burcu"
Now showing items 1-9 of 9
-
Active Subnetwork GA: A Two Stage Genetic Algorithm Approach to Active Subnetwork Search
Ozisik, Ozan; Bakir-Gungor, Burcu; Diri, Banu; Sezerman, Osman Ugur (BENTHAM SCIENCE PUBL LTDEXECUTIVE STE Y-2, PO BOX 7917, SAIF ZONE, 1200 BR SHARJAH, U ARAB EMIRATES, 2017)Background: A group of interconnected genes in a protein-protein interaction network that contains most of the disease associated genes is called an active subnetwork. Active subnetwork search is an NP-hard problem. In the ... -
Application of Biological Domain Knowledge Based Feature Selection on Gene Expression Data
Yousef, Malik; Kumar, Abhishek; Bakir-Gungor, Burcu (MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021)In the last two decades, there have been massive advancements in high throughput technologies, which resulted in the exponential growth of public repositories of gene expression datasets for various phenotypes. It is ... -
Discovering Potential Taxonomic Biomarkers of Type 2 Diabetes From Human Gut Microbiota via Different Feature Selection Methods
Bakir-Gungor, Burcu; Bulut, Osman; Jabeer, Amhar; Nalbantoglu, O. Ufuk; Yousef, Malik (FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021)Human gut microbiota is a complex community of organisms including trillions of bacteria. While these microorganisms are considered as essential regulators of our immune system, some of them can cause several diseases. In ... -
Integrating Gene Ontology Based Grouping and Ranking into the Machine Learning Algorithm for Gene Expression Data Analysis
Yousef, Malik; Sayici, Ahmet; Bakir-Gungor, Burcu (SPRINGER INTERNATIONAL PUBLISHING AGGEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND, 2021)Recent advances in the high throughput technologies resulted in the production of large gene expression data sets for several phenotypes. Via comparing the gene expression levels under different conditions, such as disease ... -
miRcorrNet: machine learning-based integration of miRNA and mRNA expression profiles, combined with feature grouping and ranking
Yousef, Malik; Goy, Gokhan; Mitra, Ramkrishna; Eischen, Christine M.; Jabeer, Amhar; Bakir-Gungor, Burcu (PEERJ INC341-345 OLD ST, THIRD FLR, LONDON EC1V 9LL, ENGLAND, 2021)A better understanding of disease development and progression mechanisms at the molecular level is critical both for the diagnosis of a disease and for the development of therapeutic approaches. The advancements in high ... -
Recursive Cluster Elimination based Rank Function (SVM-RCE-R) implemented in KNIME
Yousef, Malik; Bakir-Gungor, Burcu; Jabeer, Amhar; Goy, Gokhan; Qureshi, Rehman; C. Showe, Louise (F1000 Research Ltd, 2021)In our earlier study, we proposed a novel feature selection approach, Recursive Cluster Elimination with Support Vector Machines (SVM-RCE) and implemented this approach in Matlab. Interest in this approach has grown over ... -
Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions
Bakir-Gungor, Burcu; Moreno-Indias, Isabel; Lahti, Leo; Nedyalkova, Miroslava; Elbere, Ilze; Roshchupkin, Gennady; Adilovic, Muhamed; Aydemir, Onder; Santa Pau, Enrique Carrillo-de; D'Elia, Domenica; Desai, Mahesh S.; Falquet, Laurent; Gundogdu, Aycan; Hron, Karel; Klammsteiner, Thomas; Lopes, Marta B.; Marcos-Zambrano, Laura Judith; Marques, Claudia; Mason, Michael; May, Patrick; Pasic, Lejla; Pio, Gianvito; Pongor, Sandor; Promponas, Vasilis J.; Przymus, Piotr; Saez-Rodriguez, Julio; ampri, Alexia; Shigdel, Rajesh; Stres, Blaz; Suharoschi, Ramona; Truu, Jaak; Truica, Ciprian-Octavian; Vilne, Baiba; Vlachakis, Dimitrios; Yilmaz, Ercument; Zeller, Georg; Zomer, Aldert L.; Gomez-Cabrero, David; Claesson, Marcus J. (FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021)The human microbiome has emerged as a central research topic in human biology and biomedicine. Current microbiome studies generate high-throughput omics data across different body sites, populations, and life stages. Many ... -
SVM-RCE-R-OPT: Optimization of Scoring Function for SVM-RCE-R
Yousef, Malik; Jabeer, Amhar; Bakir-Gungor, Burcu (SPRINGER INTERNATIONAL PUBLISHING AGGEWERBESTRASSE 11, CHAM, CH-6330, SWITZERLAND, 2021)Gene expression data classification provides a challenge in classification due to it having high dimensionality and a relatively small sample size. Different feature selection approaches have been used to overcome this ... -
SYNE1 related cerebellar ataxia presents with variable phenotypes in a consanguineous family from Turkey
Yucesan, E.; Iseri, Sibel A. Ugur; Bilgic, B.; Gormez, Z.; Gungor, B. Bakir; Sarac, A.; Ozdemir, O.; Sagiroglu, M.; Gurvit, H.; Hanagasi, H.; Ozbek, U. (SPRINGER-VERLAG ITALIA SRLVIA DECEMBRIO, 28, MILAN 20137, ITALY, 2017)SYNE1 related autosomal recessive cerebellar ataxia type 1 (ARCA1) is a late-onset cerebellar ataxia with slow progression originally demonstrated in French-Canadian populations of Quebec, Canada. Nevertheless, recent ...
