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Toplam kayıt 52, listelenen: 21-30
Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics
(BEILSTEIN-INSTITUT, 2022)
Intestinal cancers are the third most lethal cancers globally, beginning as polyps in the intestine and spreading with a severe meta-static tendency. Chemotherapeutic drugs used in the treatment of intestinal tumors are ...
Comparative Genomics of Lentilactobacillus parabuchneri isolated from dairy, KEM complex, Makgeolli, and Saliva Microbiomes
(BMC, 2022)
Background: Lentilactobacillus parabuchneri is of particular concern in fermented food bioprocessing due to causing unwanted gas formation, cracks, and off-flavor in fermented dairy foods. This species is also a known ...
A subtractive proteomics approach for the identification of immunodominant Acinetobacter baumannii vaccine candidate proteins
(FRONTIERS MEDIA SA, 2022)
Background: Acinetobacter baumannii is one of the most life-threatening
multidrug-resistant pathogens worldwide. Currently, 50%–70% of clinical
isolates of A. baumannii are extensively drug-resistant, and available
antibiotic ...
Characterization of genomic, physiological, and probiotic features Lactiplantibacillus plantarum DY46 strain isolated from traditional lactic acid fermented shalgam beverage
(ELSEVIER, 2022)
Lactiplantibacillus plantarum is a significant probiotic where it could be found in ubiquitous niches. In this study, a
new Lb. plantarum strain DY46 was isolated from a traditional lactic-acid-fermented beverage called ...
WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium
(LIFE SCIENCE ALLIANCE LLC, 2023)
The correct intraflagellar transport (IFT) assembly at the ciliary base and the IFT turnaround at the ciliary tip are key for the IFT to perform its function, but we still have poor understanding about how these processes ...
Inhibition of pathologic immunoglobulin E in food allergy by EBF-2 and active compound berberine associated with immunometabolism regulation
(FRONTIERS MEDIA SA, 2023)
IntroductionFood allergy is a significant public health problem with limited treatment options. As Food Allergy Herbal Formula 2 (FAHF-2) showed potential as a food allergy treatment, we further developed a purified version ...
RPI-1 (human DCDC2) displays functional redundancy with Nephronophthisis 4 in regulating cilia biogenesis in C. elegans
(TUBİTAK, 2023)
Projecting from most cell surfaces, cilia serve as important hubs for sensory and signaling processes and have been linked to
a variety of human disorders, including Bardet-Biedl Syndrome (BBS), Meckel-Gruber Syndrome ...
Thermosensitive pluronic® F127-based in situ gel formulation containing nanoparticles for the sustained delivery of paclitaxel
(Effect Publishing Agency ( EPA ), 2023)
Bone metastasis is one of the most encountered complications among cancer patients and majority of cancer types has led to bone metastasis. Paclitaxel (PCX) is
an anticancer agent commonly used in cancer treatment. However, ...
Complementary medicines used in ulcerative colitis and unintended interactions with cytochrome P450-dependent drug-metabolizing enzymes
(TUBİTAK, 2022)
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease with multiple genetic and a variety of environmental risk
factors. Although current drugs significantly aid in controlling the disease, many people ...
Enlightening the molecular mechanisms of type 2 diabetes with a novel pathway clustering and pathway subnetwork approach
(TUBITAK, 2022)
Type 2 diabetes mellitus (T2D) constitutes 90% of the diabetes cases, and it is a complex multifactorial disease. In the last decade, genome-wide association studies (GWASs) for T2D successfully pinpointed the genetic ...