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Toplam kayıt 96, listelenen: 31-40
WDR31 displays functional redundancy with GTPase-activating proteins (GAPs) ELMOD and RP2 in regulating IFT complex and recruiting the BBSome to cilium
(LIFE SCIENCE ALLIANCE LLC, 2023)
The correct intraflagellar transport (IFT) assembly at the ciliary base and the IFT turnaround at the ciliary tip are key for the IFT to perform its function, but we still have poor understanding about how these processes ...
Inhibition of pathologic immunoglobulin E in food allergy by EBF-2 and active compound berberine associated with immunometabolism regulation
(FRONTIERS MEDIA SA, 2023)
IntroductionFood allergy is a significant public health problem with limited treatment options. As Food Allergy Herbal Formula 2 (FAHF-2) showed potential as a food allergy treatment, we further developed a purified version ...
Synthesis of nitrogen-containing oleanolic acid derivatives as carbonic anhydrase and acetylcholinesterase inhibitors
(SPRINGER BIRKHAUSER, 2023)
In this study, a total of 13 compounds (5-17) were synthesized starting from oleanolic acid (OA), a natural triterpenoid. Five new compounds (10, 11, 12, 15 and 17), are the main targets of the study, which were synthesized ...
NeRNA: A negative data generation framework for machine learning applications of noncoding RNAs
(PERGAMON-ELSEVIER SCIENCE, 2023)
Many supervised machine learning based noncoding RNA (ncRNA) analysis methods have been developed to
classify and identify novel sequences. During such analysis, the positive learning datasets usually consist of
known ...
Enkapsüle Edilmiş ve Serbest Formda Probiyotik Lactobacillus acidophilus ATCC 4356 Suşunun Dondurma Depolama Periyodunda Stabilitesinin İncelenmesi
(Atatürk Üniversitesi, 2022)
Bu çalışmada probiyotik Lb. acidophilus ATCC 4356 (ATCC 4356) suşu, ekstrüzyon yöntemi
ile aljinat kullanılarak kapsüllenmiştir. Bu enkapsüle ve serbest formdaki ATCC 4356 dondurmaya ilave edilerek −18°C’de 3 ay süre ile ...
RPI-1 (human DCDC2) displays functional redundancy with Nephronophthisis 4 in regulating cilia biogenesis in C. elegans
(TUBİTAK, 2023)
Projecting from most cell surfaces, cilia serve as important hubs for sensory and signaling processes and have been linked to
a variety of human disorders, including Bardet-Biedl Syndrome (BBS), Meckel-Gruber Syndrome ...
Thermosensitive pluronic® F127-based in situ gel formulation containing nanoparticles for the sustained delivery of paclitaxel
(Effect Publishing Agency ( EPA ), 2023)
Bone metastasis is one of the most encountered complications among cancer patients and majority of cancer types has led to bone metastasis. Paclitaxel (PCX) is
an anticancer agent commonly used in cancer treatment. However, ...
Complementary medicines used in ulcerative colitis and unintended interactions with cytochrome P450-dependent drug-metabolizing enzymes
(TUBİTAK, 2022)
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease with multiple genetic and a variety of environmental risk
factors. Although current drugs significantly aid in controlling the disease, many people ...
Investigation of Antiviral Potential of Food Carotenoids and Apocarotenoids against RNA-dependent RNA Polymerase of Hepatitis C Virus
(Bitlis Eren Üniversitesi, 2022)
Hepatitis C disease have been a global health threat and affects a significant portion of world population. Hepatitis C have also been a silent health threat for Turkiye, where there are around half million people infected ...
RNA İkincil Yapılarının Çok Boyutlu Gösterimi ve Pre-Mirna Tespiti Için Uygulamaları
(TUBİTAK, 2021)
MikroRNA'lar (miRNA'lar), transkripsiyon sonrası gen ekspresyonu düzenleyicileridir. Bir
miRNA yüzlerce haberci RNA'yı (mRNA'lar) hedefleyebildiği gibi, bir mRNA farklı miRNA'lar
tarafından hedeflenebilir, üstelik tek ...