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Toplam kayıt 1767, listelenen: 1645-1664
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The therapeutic potential of targeting HDAC6 with Tubastatin A in TFK-1 and EGI-1 cholangiocarcinoma cells
(SİVAS CUMHURİYET ÜNİVERSİTESİ: Sivas Cumhuriyet University, 2021)Cholangiocarcinoma (CCA) is a highly aggressive and invasive malignancy with a poor diagnosis because of the resistance, relapse and limited therapy. Histone deacetylases (HDAC) are a class of enzyme that have important ... -
Therapeutic Targeting of FLT3 in Acute Myeloid Leukemia: Current Status and Novel Approaches
(Dove Medical Press Ltd, 2022)FMS-like tyrosine kinase 3 (FLT3) is mutated in approximately 30% of acute myeloid leukemia (AML) patients. The presence of FLT3-ITD (internal tandem duplication, 20–25%) mutation and, to a lesser extent, FLT3-TKD (tyrosine ... -
Thermal conductivity and interfacial energy of solid Bi in the Bi-Ag eutectic system
(SPRINGER, 2015)The equilibrated grain boundary groove shapes for solid Bi (Bi–2.87 at.%Ag) in equilibrium with Bi–Ag eutectic liquid have been observed from quenched sample with a radial heat flow apparatus. The Gibbs–Thomson coefficient, ... -
Thermal conductivity, compressive strength and ultrasonic wave velocity of cementitious composite containing waste PET lightweight aggregate (WPLA)
(ELSEVIER SCI LTD, 2013)In this study, the influence of waste PET as lightweight aggregate (WPLA) replacement with conventional aggregate, on thermal conductivity, unit weight and compressive strength properties of concrete composite was ... -
Thermal stresses in SOFC stacks: the role of mismatch among thermal conductivity of adjacent components
(SCIENTIFIC TECHNICAL RESEARCH COUNCIL TURKEY-TUBITAKATATURK BULVARI NO 221, KAVAKLIDERE, TR-06100 ANKARA, TURKEY, 2021)Generating power from renewable biogas in solid oxide fuel cells (SOFCs) is an environment-friendly, efficient, and promising energy conversion process. Biogas can be used in SOFCs via a reforming process for which dry ... -
Thermo-Responsive Complexes of c-Myc Antisense Oligonucleotide with Block Copolymer of Poly(OEGMA) and Quaternized Poly(4-Vinylpyridine)
(WILEY-V C H VERLAG GMBHPOSTFACH 101161, 69451 WEINHEIM, GERMANY, 2017)Solution behavior of thermo-responsive polymers and their complexes with biological macromolecules may be affected by environmental conditions, such as the concentration of macromolecular components, pH, ion concentration, ... -
Thermochemistry of alkali metal cation interactions with histidine: Influence of the side chain
(American Chemical Society, 2012)The interactions of alkali metal cations (M+ = Na+ , K+ , Rb+ , Cs+ ) with the amino acid histidine (His) are examined in detail. Experimentally, bond energies are determined using threshold collision-induced ... -
Thermosensitive pluronic® F127-based in situ gel formulation containing nanoparticles for the sustained delivery of paclitaxel
(Effect Publishing Agency ( EPA ), 2023)Bone metastasis is one of the most encountered complications among cancer patients and majority of cancer types has led to bone metastasis. Paclitaxel (PCX) is an anticancer agent commonly used in cancer treatment. However, ... -
Thickness-Tunable Self-Assembled Colloidal Nanoplatelet Films Enable Ultrathin Optical Gain Media
(AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2020)We propose and demonstrate construction of highly uniform, multilayered superstructures of CdSe/CdZnS core/shell colloidal nanoplatelets (NPLs) using liquid interface self-assembly. These NPLs are sequentially deposited ... -
Thin films of inert metal nanowires for display applications
(TANGER LTD, 2015)Ag nanowire transparent electrode has excellent transmittance (90%) and sheet resistance (20 Ohm/sq), yet there are slight drawbacks such as optical haze and chemical instability against aerial oxidation. Chemical stability ... -
Three dimensional patient-specific guides for guide pin positioning in reverse shoulder arthroplasty: An experimental study on different glenoid types
(SAGE PUBLICATIONS LTD1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND, 2022)Introduction Incorrect positioning is one of the main factors for glenoid component loosening in reverse shoulder arthroplasty and component placement can be challenging. This study aimed to assess whether Patient-Specific ... -
Three dimensional stress analysis of solid oxide fuel cell anode micro structure
(PERGAMON-ELSEVIER SCIENCE LTD, 2014)One of the most common problems in solid oxide fuel cells (SOFCs) is the delamination and thus the degradation of electrode/electrolyte interface which occurs in the consequences of the stresses generated within the ... -
Three-Dimensional Au-Coated Electrosprayed Nanostructured BODIPY Films on Aluminum Foil as Surface-Enhanced Raman Scattering Platforms and Their Catalytic Applications
(AMER CHEMICAL SOC1155 16TH ST, NW, WASHINGTON, DC 20036, 2017)The design and development of three-dimensional (3D) nanostructures with high surface-enhanced Raman scattering (SERS) performances have attracted considerable attention in the fields of chemistry, biology, and materials ... -
Three-dimensional imaging in degraded visual field
(Institute of Physics Publishing, 2016)Imaging at degraded visual environments is one of the biggest challenges in today's imaging technologies. Especially military and commercial rotary wing aviation is suffering from impaired visual field in sandy, dusty, ... -
Time-Dependent Reduction of Calcium Oscillations in Adipose-Derived Stem Cells Differentiating towards Adipogenic and Osteogenic Lineage
(MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021)Adipose-derived mesenchymal stromal cells (ASCs) are multipotent stem cells which can differentiate into various cell types, including osteocytes and adipocytes. Due to their ease of harvesting, multipotency, and low ... -
A toolbox of machine learning software to support microbiome analysis
(Frontiers Media SA, 2023)The human microbiome has become an area of intense research due to its potential impact on human health. However, the analysis and interpretation of this data have proven to be challenging due to its complexity and ... -
A Top-Down Approach for Finding Affected Pathway Subnetworks in Type 2 Diabetes
(IEEE, 2020)Diyabet (Diabetes Mellitus, DM), insülin üreten pankreas beta hücrelerindeki fonksiyon bozukluğu, insülin direnci veya insülinin işlevselliğinin bozulması ile meydana gelen bir tür metabolik bozukluktur. Diyabet vakalarının ... -
Topological feature generation for link prediction in biological networks
(PEERJ INC, 2023)Graph or network embedding is a powerful method for extracting missing or potential information from interactions between nodes in biological networks. Graph embedding methods learn representations of nodes and interactions ... -
Toward sustainable optoelectronics: solution-processed quantum dot photodetector fabrication using a surgical blade
(SPIE-SOC PHOTO-OPTICAL INSTRUMENTATION ENGINEERS, 2023)Fabrication of optoelectronic devices relies on expensive, energy-consuming conventional tools including chemical vapor deposition, lithography, and metal evaporation. Furthermore, the films used in these devices are usually ... -
Towards Analysis and Optimization for Contact Zone Temperature Changes and Specific Wear Rate of Metal Matrix Composite Materials Produced from Recycled Waste
(MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2021)Tribological properties are important to evaluate the in-service conditions of machine elements, especially those which work as tandem parts. Considering their wide range of application areas, metal matrix composites (MMCs) ...
