Ara
Toplam kayıt 126, listelenen: 111-120
Akut Myeloid Lösemi Tedavisi için Hedgehog Ve Otofaji Yolaklarının Düzenlenmesi
(TUBİTAK, 2019)
Akut myeloid lösemi (AML) çeşitli moleküler aberasyonlar ve sinyal yolaklarındaki bozuklukları
içeren klonal hastalıklar ile karakterize edilen bir grup heterojen malignanttır. Hedgehog (HH)
sinyal yolağı birçok kanserde ...
Comparison of Mechanical and Physical Properties of Screed with and without Expanded Polystyrene (EPS) Particles
(YILDIZ TEKNİK ÜNİVERSİTESİ, 2022)
In this study, in order to observe the mechanical and physical properties of ordinary screed, sandy-lightweight screed and lightweight screed samples, expanded polystyrene (EPS) was used as fine aggregate and lightweight ...
PACLITAXEL-LOADED POLYCAPROLACTONE NANOPARTICLES FOR LUNG TUMORS; FORMULATION, COMPREHENSIVE IN VITRO CHARACTERIZATION AND RELEASE KINETIC STUDIES
(Ankara Üniversitesi, 2022)
Objective: Today, cancer is still among the most common chronic diseases. Nanoparticular drug delivery systems prepared with biocompatible and biodegradable polymers such as polycaprolactone are rational solution for ...
Combined effect of midostaurin and sphingosine kinase-1 inhibitor on FMS-like tyrosine kinase 3 (FLT3) wild type acute myeloid leukemia cells
(De Gruyter, 2022)
Objectives Therapeutic potential of clinically approved FLT3 inhibitor midostaurin has been neglected in wild-type FLT3 positive acute myeloid leukemia (AML). Sphingosine kinase-1 (SK-1) having anti-proliferative functions ...
Evaluating the microbial growth kinetics and artificial gastric digestion survival of a novel Pichia kudriavzevii FOL-04
(TAGEM Journals, 2022)
Present study aims to explore Pichia kudriavzevii FOL-04 (FOL-04)’s: i) survival against artificial gastric juice (AGJ) and artificial bile juice (ABJ), ii) growth kinetics in shake flask (SF) and fed-batch trials (FBT). ...
Cytotoxic and Cytostatic Effects of Targeting mTOR and Hedgehog Pathways in Acute Myeloid Leukemia
(İstanbul Üniversitesi Yayınevi, 2022)
Objectives: Acute myeloid leukemia (AML) is a highly aggressive heterogeneous hematopoietic malignancy characterized by a rapid
and abnormal proliferation of immature myeloid leukemia cells in the bone marrow and peripheral ...
EXTRACTION OF LANTHANUM AND CERIUM FROM A BASTNASITE ORE BY DIRECT ACIDIC LEACHING
(TÜBİTAK ULAKBİM Ulusal Akademik Ağ ve Bilgi Merkezi Cahit Arf Bilgi Merkezi, 2020)
The extraction of lanthanum (La) and cerium (Ce) from a bastnasite ore by direct acidic leaching was investigated. The effects of acid concentration and leaching temperature on the extraction of La and Ce from the ore were ...
ZEOLITE SYNTHESIS BY ALKALI FUSION METHOD USING TWO DIFFERENT FLY ASHES DERIVED FROM TURKISH THERMAL POWER PLANTS
(TÜBİTAK ULAKBİM Ulusal Akademik Ağ ve Bilgi Merkezi Cahit Arf Bilgi Merkezi, 2020)
In this study, Faujasite (Na-LSX) (3.5(Ca0.3)3.5(Na0.6)3.5(Mg0.1)Al7Si17O48•32(H2O)) type zeolites and Ca-Filipsite (CaK0.6Na0.4Si5.2Al2.8O16•6(H2O)) type zeolites were produced from Sugözü Thermal Power Plant and Çatalağzı ...
UNDERSTANDING INTANGIBLE ASPECTS OF CULTURAL LANDSCAPE; LIVING CULTURES OF NORTHEAST KAYSERI VALLEYS
(GELENEKSEL YAYINCILIK LTD STLGAZI MAH CAKIR SOK, 21-5 YENIMAHALLE, ANKARA, TURKEY, 2021)
Sustaining cultural landscapes requires the conservation of socio-cultural characteristics as well as their physical manifestations. It is essential to document and conserve tangible and intangible elements of heritage in ...
Apatinib Sensitizes Human Breast Cancer Cells against Navitoclax and Venetoclax Despite Up-regulated Bcl-2 and Mcl-1 Gene Expressions
(KARE PUBLCONCORD ISTANBUL, DUMLUPINAR MAH, CIHAN SK NO 15, B BLOK 162 KADIKOY, ISTANBUL, TURKEY, 2021)
OBJECTIVE
Defects in apoptotic cell death which restrict the success of conventional cytotoxic therapies have pivotal roles in a number of pathological conditions including cancer. However, a novel drug class targeting ...