Browsing PubMed İndeksli Yayınlar Koleksiyonu by Title
Now showing items 63-82 of 256
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A decision support system for the prediction of mortality in patients with acute kidney injury admitted in intensive care unit
(UNIV SOUTH BOHEMIA, FAC HEALTH & SOCIAL STUD, JIROVCOVA, CESKA BUDEJOVICE, 370 04, CZECH REPUBLIC, 2020)Intensive care unit (ICU) is a very special unit of a hospital, where healthcare professionals provide treatment and, later, close followup to the patients. It is crucial to estimate mortality in ICU patients from many ... -
The design and fabrication of supramolecular semiconductor nanowires formed by benzothienobenzothiophene (BTBT)-conjugated peptides
(Royal Society of Chemistry, 2018)?-Conjugated small molecules based on a [1]benzothieno[3,2-b]benzothiophene (BTBT) unit are of great research interest in the development of solution-processable semiconducting materials owing to their excellent charge-transport ... -
Determination of promising inhibitors for N-SH2 domain of SHP2 tyrosine phosphatase: an in silico study
(SPRINGER NATURE LINK, 2024)There are many genes that produce proteins related to diseases and these proteins can be targeted with drugs as a potential therapeutic approach. Recent advancement in drug discovery techniques have created new opportunities ... -
Development of a Nanoparticle-Embedded Chitosan Sponge for Topical and Local Administration of Chemotherapeutic Agents
(American Society of Mechanical Engineers (ASME), 2014)The following work describes the development of a novel noninvasive transmucosal drug delivery system, the chitosan sponge matrix (CSM). It is composed of cationic chitosan (CS) nanoparticles (NPs) that encapsulate cisplatin ... -
Dicarboxylic Acids Induced Tandem Transformation of Silver Nanocluster
(AMER CHEMICAL SOC, 2023)Structural transformation of metal nanoclusters (NCs) is of great ongoing interest regarding their synthesis, stability, and reactivity. Although sporadic examples of cluster transformations have been reported, neither ... -
Differential in vitro anti-leukemic activity of resveratrol combined with serine palmitoyltransferase inhibitor myriocin in FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) carrying AML cells
(SPRINGER, 2022)Treatment of FMS-like tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) AML is restricted due to toxicity, drug resistance and relapse eventhough targeted therapies are clinically available. Resveratrol with its ... -
Discovering Potential Taxonomic Biomarkers of Type 2 Diabetes From Human Gut Microbiota via Different Feature Selection Methods
(FRONTIERS MEDIA SAAVENUE DU TRIBUNAL FEDERAL 34, LAUSANNE CH-1015, SWITZERLAND, 2021)Human gut microbiota is a complex community of organisms including trillions of bacteria. While these microorganisms are considered as essential regulators of our immune system, some of them can cause several diseases. In ... -
Discovery of adapalene and dihydrotachysterol as antiviral agents for the Omicron variant of SARS‑CoV‑2 through computational drug repurposing
(SPRINGER, VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, 2022)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been signifcantly paralyzing the societies, economies and health care systems around the globe. The mutations on the genome of SARS-CoV-2 led to the emergence ... -
Draft genome of carotenoid-producing endophytic Pseudomonas sp. 102515 from Taxus chinensis
(American Society for Microbiology, 2024)Here, we report the draft genome sequence of endophytic Pseudomonas sp. 102515 isolated from Taxus chinensis collected from Logan, UT, USA. The genome is composed of 36 contigs and around 4.9 Mbp in size. The GC content ... -
Dual Targeting of DNA Damage Response Proteins Implicated in Cancer Radioresistance
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Ionizing radiation can induce different types of DNA lesions, leading to genomic instability and ultimately cell death. Radiation therapy or radiotherapy, a major modality in cancer treatment, harnesses the genotoxic ... -
Editorial: Microbial production of medicinally important agents
(FRONTIERS MEDIA SA, 2023)Harnessing microbial systems as bio-factories for the production of medically significant agents presents a thriving avenue in pharmaceutical research. From manufacturing natural products, including potent secondary ... -
Effect of Calcium Oxide on Stress Crack Resistance and Light Transmittance in PET Containers for Packaging Carbonated Beverages
(AMER CHEMICAL SOC, 2024)For polyethylene terephthalate (PET) bottles, a material used for food packaging, light transmission and mechanical performance, particularly environmental stress cracking (ESC), are essential characteristics. For this ... -
The effect of lockdown on students' performance: A comparative study between Italy, Sweden and Turkey
(ELSEVIER SCI LTD, 2023)During the first months of the COVID-19 outbreak, countries adopted different strategies in order to mitigate the effects of the pandemic, ranging from recommendations to limit individual movement to severe lockdown measures. ... -
An effective colorectal polyp classification for histopathological images based on supervised contrastive learning
(ELSEVIER, 2024)Early detection of colon adenomatous polyps is pivotal in reducing colon cancer risk. In this context, accurately distinguishing between adenomatous polyp subtypes, especially tubular and tubulovillous, from hyperplastic ... -
Effective Neural Photostimulation Using Indium-Based Type-II Quantum Dots
(AMER CHEMICAL SOC, 1155 16TH ST, NW, WASHINGTON, DC 20036 USA, 2018)Light-induced stimulation of neurons via photoactive surfaces offers rich opportunities for the development of therapeutic methods and high-resolution retinal prosthetic devices. Quantum dots serve as an attractive building ... -
Effects of cell-mediated osteoprotegerin gene transfer and mesenchymal stem cell applications on orthodontically induced root resorption of rat teeth
(OXFORD UNIV PRESS, GREAT CLARENDON ST, OXFORD OX2 6DP, ENGLAND, 2017)Aim: The aim of this study is to evaluate and compare therapeutic effects of mesenchymal stem cell (MSCs) and osteoprotegerin (OPG) gene transfer applications on inhibition and/or repair of orthodontically induced inflammatory ... -
Effects of COVID-19 on Adolescent Mental Health and Internet Use by Ethnicity and Gender: A Mixed-Method Study
(MDPIST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND, 2022)Evidence suggests that mental health problems in young people have been exacerbated by COVID-19, possibly related to a lack of social connection. Young people report using the internet for connecting with their peers and ... -
Elucidating the complex membrane binding of a protein with multiple anchoring domains using extHMMM
(Public Library of Science, 2024)Membrane binding is a crucial mechanism for many proteins, but understanding the specific interactions between proteins and membranes remains a challenging endeavor. Coagulation factor Va (FVa) is a large protein whose ... -
Emerging DNA Methylome Targets in FLT3-ITD-Positive Acute Myeloid Leukemia: Combination Therapy with Clinically Approved FLT3 Inhibitors
(SPRINGER LINK, 2024)The internal tandem duplication (ITD) mutation of the FMS-like receptor tyrosine kinase 3 (FLT3-ITD) is the most common mutation observed in approximately 30% of acute myeloid leukemia (AML) patients. It represents poor ... -
Enhancing the Properties of Yttria-Stabilized Zirconia Composites with Zeolitic Imidazolate Framework-Derived Nanocarbons
(AMER CHEMICAL SOC, 2023)Ceramic matrix composites (CMCs) reinforced with nanocarbon have attracted significant interest due to their potential to enhance mechanical, thermal, and electrical properties. Although the investigation of carbon-based ...
