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Toplam kayıt 21, listelenen: 1-10
Centella asiatica extract containing bilayered electrospun wound dressing
(Abdullah Gül Üniversitesi, 2019)
Innovative and bioactive wound dressings prepared by electrospinning mimicking the native structure of the extracellular matrix (ECM) have gained significant interest as an alternative to conventional wound care applications. ...
The effect of hedgehog inhibition and autophagy modulation on the proliferation and survival of AML cell lines /
(2019)
Acute myeloid leukemia (AML) is a heterogeneous hematopoietic malignancy which occurs as a result of many chromosomal abnormalities such as translocations, deletions or insertions. Aberrant signaling pathways such as ...
Immunomagnetic separation and immobilization of leukemia cells using cell surface markers /
(Abdullah Gül Üniversitesi, 2017)
Acute Lympoblastic Leukemia, shortly ALL, especially B-precursor Acute Lymphoblastic Leukemia is the most common blood malignancies among childhood cancers. There are different kinds of leukemia treatments but after those ...
The inhibition of autophagy and hedgehog pathway leads to a decrease in the proliferation of cholangiocarcinoma
(Abdullah Gül Üniversitesi, 2019)
Cholangiocarcinoma (CCA) is the second most common liver cancer type. The median survival rate of CCA patients is really low. Aberrant signaling pathways such as PI3K/AKT/mTOR pathway could be main drivers in CCA pathogenesis. ...
INVESTIGATION OF NEW CILIOPATHY GENES
(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2021)
Kirpikler, iç yapısında mikrotübüllerden oluşur ve evrimsel olarak anten benzeri bir organel korunmuştur. Kirpik yapısındaki bozuklukların neden olduğu hastalığa siliyopati adı verilir ve Joubert sendromu siliyopatilerden ...
CHARACTERIZATION OF NOVEL CILIARY GENE TMEM145
(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2020)
Cilia and flagella are highly conserved, microtubule based cellular structures which are
found in most of the organisms. They have variety of functions from enabling movement
in protozoa to signal transduction in multi ...
A BIOMIMETIC APPROACH FOR SMALL DIAMETER VESSELS: BILAYERED VASCULAR GRAFTS MADE of ALGINATE and POLY(-CAPROLACTONE)
(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2019)
Cardiovascular diseases (CVDs) still remain one of the leading causes of morbidity and mortality across the world. A typical symptom of CVDs is the vascular occlusion. There are many strategies for treatment such as ...
DEVELOPMENT OF A LOW-COST MICROFLUIDIC SYSTEM TO DETECT IMMUNOMAGNETICALLY CAPTURED LEUKEMIA CELLS
(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2020)
Sensör teknolojileri fiziksel özellikleri ölçülebilir sinyallere dönüştürmek için kullanılır. Özellikle yarı iletken teknolojisindeki gelişmelerle birlikte, mikroakışkan olarak bilinen yeni bir teknoloji ortaya çıktı. ...
DEVELOPMENT OF A KIDNEY TARGETTED NANOCARRIER FORMULATION AGAINST CISPLATIN INDUCED NEPHROTOXICITY
(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2019)
Chitosan is a natural polymer which is less toxic in the body than other synthetic
polymers. Chitosan sodium tripolyphosphate (TPP) nanoparticles produced by ionic
gelation method are known to be good drug delivery agents ...
THE EFFECT OF HISTONE DEACETYLASE INHIBITORS ON PTEN/PI3K/AKT/mTOR PATHWAY AND THE CARCINOGENESIS OF CHEMORESISTANT CHOLANGIOCARCINOMA AT A MOLECULAR LEVEL
(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2021)
Kolanjiokarsinom (CCA) agresif bir adenokarsinomdur ve ikinci en sık görülen birincil karaciğer tümörüdür. CCA gelişiminin kesin etiyolojisi hala net olarak tanımlanmamıştır. Mevcut kemoterapötik tedaviler, çoklu ilaç ...