Ara
Toplam kayıt 42, listelenen: 21-30
Enlightening the molecular mechanisms of type 2 diabetes with a novel pathway clustering and pathway subnetwork approach
(TUBITAK, 2022)
Type 2 diabetes mellitus (T2D) constitutes 90% of the diabetes cases, and it is a complex multifactorial disease. In the last decade, genome-wide association studies (GWASs) for T2D successfully pinpointed the genetic ...
The therapeutic potential of targeting HDAC6 with Tubastatin A in TFK-1 and EGI-1 cholangiocarcinoma cells
(SİVAS CUMHURİYET ÜNİVERSİTESİ: Sivas Cumhuriyet University, 2021)
Cholangiocarcinoma (CCA) is a highly aggressive and invasive malignancy with a poor diagnosis because of the resistance, relapse and limited therapy. Histone deacetylases (HDAC) are a class of enzyme that have important ...
Microfluidic Devices: A New Paradigm in Toxicity Studies
(Hacettepe Üniversitesi, 2020)
In recent years, great emphasis has been placed on non-animal toxicological methods (e.g. in vitro models, in silico or −omicsdata) as alternative strategies to reduce animal-testing, in line with the 3R (Replacement, ...
Editorial: Microbial production of medicinally important agents
(FRONTIERS MEDIA SA, 2023)
Harnessing microbial systems as bio-factories for the production of medically significant
agents presents a thriving avenue in pharmaceutical research. From manufacturing natural
products, including potent secondary ...
Berberine-containing natural-medicine with boiled peanut-OIT induces sustained peanut-tolerance associated with distinct microbiota signature
(FRONTIERS MEDIA SA, 2023)
BackgroundGut microbiota influence food allergy. We showed that the natural compound berberine reduces IgE and others reported that BBR alters gut microbiota implying a potential role for microbiota changes in BBR function. ...
CiliaMiner: an integrated database for ciliopathy genes and ciliopathies
(OXFORD UNIV PRESS, 2023)
Cilia are found in eukaryotic species ranging from single-celled organisms, such as Chlamydomonas reinhardtii, to humans, but not
in plants. The ability to respond to repellents and/or attractants, regulate cell proliferation ...
GeNetOntology: identifying affected gene ontology terms via grouping, scoring, and modeling of gene expression data utilizing biological knowledge-based machine learning
(FRONTIERS MEDIA SA, 2023)
Introduction: Identifying significant sets of genes that are up/downregulated under specific conditions is vital to understand disease development mechanisms at the molecular level. Along this line, in order to analyze ...
Histopathology image classification: highlighting the gap between manual analysis and AI automation
(FRONTIERS MEDIA SA, 2023)
The field of histopathological image analysis has evolved significantly with the advent of digital pathology, leading to the development of automated models capable of classifying tissues and structures within diverse ...
A comprehensive study on automatic non-informative frame detection in colonoscopy videos
(WILEY, 2024)
Despite today's developing healthcare technology, conventional colonoscopy is still a gold-standard method to detect colon abnormalities. Due to the folded structure of the intestine and visual disturbances caused by ...
Comparative genomics of Loigolactobacillus coryniformis with an emphasis on L. coryniformis strain FOL-19 isolated from cheese
(ELSEVIER, 2023)
Loigolactobacillus coryniformis is a member of lactic acid bacteria isolated from various ecological niches. We isolated a novel L. coryniformis strain FOL-19 from artisanal Tulum cheese and performed the whole-genome ...