Ara
Toplam kayıt 47, listelenen: 21-30
RPI-1 (human DCDC2) displays functional redundancy with Nephronophthisis 4 in regulating cilia biogenesis in C. elegans
(TUBİTAK, 2023)
Projecting from most cell surfaces, cilia serve as important hubs for sensory and signaling processes and have been linked to
a variety of human disorders, including Bardet-Biedl Syndrome (BBS), Meckel-Gruber Syndrome ...
Thermosensitive pluronic® F127-based in situ gel formulation containing nanoparticles for the sustained delivery of paclitaxel
(Effect Publishing Agency ( EPA ), 2023)
Bone metastasis is one of the most encountered complications among cancer patients and majority of cancer types has led to bone metastasis. Paclitaxel (PCX) is
an anticancer agent commonly used in cancer treatment. However, ...
Investigation of Antiviral Potential of Food Carotenoids and Apocarotenoids against RNA-dependent RNA Polymerase of Hepatitis C Virus
(Bitlis Eren Üniversitesi, 2022)
Hepatitis C disease have been a global health threat and affects a significant portion of world population. Hepatitis C have also been a silent health threat for Turkiye, where there are around half million people infected ...
RNA İkincil Yapılarının Çok Boyutlu Gösterimi ve Pre-Mirna Tespiti Için Uygulamaları
(TUBİTAK, 2021)
MikroRNA'lar (miRNA'lar), transkripsiyon sonrası gen ekspresyonu düzenleyicileridir. Bir
miRNA yüzlerce haberci RNA'yı (mRNA'lar) hedefleyebildiği gibi, bir mRNA farklı miRNA'lar
tarafından hedeflenebilir, üstelik tek ...
Enlightening the molecular mechanisms of type 2 diabetes with a novel pathway clustering and pathway subnetwork approach
(TUBITAK, 2022)
Type 2 diabetes mellitus (T2D) constitutes 90% of the diabetes cases, and it is a complex multifactorial disease. In the last decade, genome-wide association studies (GWASs) for T2D successfully pinpointed the genetic ...
The therapeutic potential of targeting HDAC6 with Tubastatin A in TFK-1 and EGI-1 cholangiocarcinoma cells
(SİVAS CUMHURİYET ÜNİVERSİTESİ: Sivas Cumhuriyet University, 2021)
Cholangiocarcinoma (CCA) is a highly aggressive and invasive malignancy with a poor diagnosis because of the resistance, relapse and limited therapy. Histone deacetylases (HDAC) are a class of enzyme that have important ...
Microfluidic Devices: A New Paradigm in Toxicity Studies
(Hacettepe Üniversitesi, 2020)
In recent years, great emphasis has been placed on non-animal toxicological methods (e.g. in vitro models, in silico or −omicsdata) as alternative strategies to reduce animal-testing, in line with the 3R (Replacement, ...
Yara Örtü Malzemesi Olarak Elektroeğrilmiş PCL/PHBV Membranların Hazırlanması ve Karakterizasyonu
(Bitlis Eren Üniversitesi, 2019)
Bu çalışmada, yara örtü malzemesi olarak polikaprolakton (PCL), poli(3-hidroksibütirik asit-ko-3-hidroksivalerikasit) (PHBV) ve ağırlıkça farklı oranlarda (100:0, 50:50, 75:25, 0:100) PCL/PHBV karışımları, farklı ...
Editorial: Microbial production of medicinally important agents
(FRONTIERS MEDIA SA, 2023)
Harnessing microbial systems as bio-factories for the production of medically significant
agents presents a thriving avenue in pharmaceutical research. From manufacturing natural
products, including potent secondary ...
Berberine-containing natural-medicine with boiled peanut-OIT induces sustained peanut-tolerance associated with distinct microbiota signature
(FRONTIERS MEDIA SA, 2023)
BackgroundGut microbiota influence food allergy. We showed that the natural compound berberine reduces IgE and others reported that BBR alters gut microbiota implying a potential role for microbiota changes in BBR function. ...