Yazar "Gencer Akçok, Emel Başak" için listeleme
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Inhibition of PI3K-AKT-mTOR pathway and modulation of histone deacetylase enzymes reduce the growth of acute myeloid leukemia cells
Şansaçar, Merve; Sağır, Helin; Gencer Akçok, Emel Başak (HUMANA PRESS INC, 2023)One of the most widespread forms of blood cancer is known as acute myeloid leukemia (AML) which has an incidence of 80% with poor prognosis. Although there are different treatment methods for AML in clinic, the heterogeneity ... -
The therapeutic potential of targeting HDAC6 with Tubastatin A in TFK-1 and EGI-1 cholangiocarcinoma cells
Yenigül, Münevver; Gencer Akçok, Emel Başak (SİVAS CUMHURİYET ÜNİVERSİTESİ: Sivas Cumhuriyet University, 2021)Cholangiocarcinoma (CCA) is a highly aggressive and invasive malignancy with a poor diagnosis because of the resistance, relapse and limited therapy. Histone deacetylases (HDAC) are a class of enzyme that have important ... -
Tomatidine, a Steroidal Alkaloid, Synergizes with Cisplatin to Inhibit Cell Viability and Induce Cell Death Selectively on FLT3-ITD+ Acute Myeloid Leukemia Cells
Ayvaz, Havva Berre; Yenigül, Münevver; Gencer Akçok, Emel Başak (SPRINGER NATURE Link, 2024)Background: Acute Myeloid Leukemia (AML) is a hematological cancer that frequently presents with a range of side effects and drug resistance during anticancer drug treatment. The current study aims to achieve increased ...
