Güncel Gönderiler: Biyomühendislik Ana Bilim Dalı Tez Koleksiyonu
Toplam kayıt 26, listelenen: 21-26
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THERAPEUTIC POTENTIAL OF RESVERATROL AND THE ROLE OF CERAMIDE METABOLISM IN RESVERATROL-TRIGGERED APOPTOSIS IN FLT3+ ACUTE MYELOID LEUKEMIA
(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2021)Resveratrol’ün FLT3-ITD+ AML hücreleri üzerindeki büyüme engelleyici etkilerinin altında yatan mekanizmalar, seramid metabolizması hedeflenerek araştırıldı. Resveratrol, SK (sfingosin kinaz) inhibitörü (SKI II), GCS ... -
INVESTIGATION OF NEW CILIOPATHY GENES
(Abdullah Gül Üniversitesi, Fen Bilimleri Enstitüsü, 2021)Kirpikler, iç yapısında mikrotübüllerden oluşur ve evrimsel olarak anten benzeri bir organel korunmuştur. Kirpik yapısındaki bozuklukların neden olduğu hastalığa siliyopati adı verilir ve Joubert sendromu siliyopatilerden ... -
Centella asiatica extract containing bilayered electrospun wound dressing
(Abdullah Gül Üniversitesi, 2019)Innovative and bioactive wound dressings prepared by electrospinning mimicking the native structure of the extracellular matrix (ECM) have gained significant interest as an alternative to conventional wound care applications. ... -
The effect of hedgehog inhibition and autophagy modulation on the proliferation and survival of AML cell lines /
(2019)Acute myeloid leukemia (AML) is a heterogeneous hematopoietic malignancy which occurs as a result of many chromosomal abnormalities such as translocations, deletions or insertions. Aberrant signaling pathways such as ... -
The inhibition of autophagy and hedgehog pathway leads to a decrease in the proliferation of cholangiocarcinoma
(Abdullah Gül Üniversitesi, 2019)Cholangiocarcinoma (CCA) is the second most common liver cancer type. The median survival rate of CCA patients is really low. Aberrant signaling pathways such as PI3K/AKT/mTOR pathway could be main drivers in CCA pathogenesis. ... -
Immunomagnetic separation and immobilization of leukemia cells using cell surface markers /
(Abdullah Gül Üniversitesi, 2017)Acute Lympoblastic Leukemia, shortly ALL, especially B-precursor Acute Lymphoblastic Leukemia is the most common blood malignancies among childhood cancers. There are different kinds of leukemia treatments but after those ...