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dc.contributor.authorAksebzeci, Bekir Hakan
dc.contributor.authorKayaaltı, Seda
dc.contributor.authorKayaaltı, Ömer
dc.date.accessioned2019-06-25T06:40:10Z
dc.date.available2019-06-25T06:40:10Z
dc.date.issued2018en_US
dc.identifier.issn2602-2974
dc.identifier.otherDOI: 10.4274/tybd.86158
dc.identifier.otherAccession Number: WOS:000452006700004
dc.identifier.otherIDS Number: HC7UI
dc.identifier.urihttp://acikerisim.agu.edu.tr/xmlui/handle/20.500.12573/14
dc.description.abstractObjective: Almost half of intensive care patients are affected by acute kidney injury (AKI). The purpose of this study is to determine parameters that can be used for predicting of early (within 28 days) and late (within 90 days) mortality in patients who are followed-up with AKI in intensive care units. Materials and Methods: In this study, a dataset that contains 50 patients with AKI in intensive care units was used. This dataset contains blood urea nitrogen, creatinine, plasma and urinary neutrophil gelatinase-associated hpocalin (NGAL), lactate dehydrogenase, alkaline phosphatase and gammaglutamyl transpeptidase values of patients who were admitted to intensive care for various reasons and who developed AKI on the days 1, 3 and 7. In addition to these values, laboratory results such as serum electrolytes on day 1, blood gas; vital signs such as mean arterial pressure, central venous pressure; and demographic data were also recorded. Data mining techniques were applied to determine correlation between all of these data and mortality. Results: The threshold level of urinary NGAL on day 7 was determined to be 69 ng/mL, and strong correlation was found between this threshold level and early mortality. Similarly, the threshold level of plasma NGAL on day 7 was determined to be 150 ng/mL, and this was highly correlated with early mortality. Besides, strong correlation was also found between the difference in the urinary NGAL levels on day 1 and 7, and early mortality. Conclusion: In this study, plasma and urinary NGAL levels were found to be closely related to early mortality in patients who were followed-up with AKI in intensive care units. On the other hand, any parameter associated with late mortality was not found.en_US
dc.language.isoturen_US
dc.publisherGALENOS YAYINCILIK, ERKAN MOR, MOLLA GURANI CAD 21-1, FINDIKZADE, ISTANBUL 34093, TURKEYen_US
dc.relation.ispartofseriesTURKISH JOURNAL OF INTENSIVE CARE-TURK YOGUN BAKIM DERGISI;Volume: 16 Issue: 3 Pages: 101-108
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute kidney injuryen_US
dc.subjectplasma NGALen_US
dc.subjecturinary NGALen_US
dc.subjectmortalityen_US
dc.subjectdata miningen_US
dc.titleAkut Böbrek Hasarında Nötrofil Jelatinaz İlişkili Lipokalin ile Mortalite İlişkisien_US
dc.title.alternativeRelationship Between Neutrophil Gelatinase-associated Lipocalin and Mortality in Acute Kidney Injury
dc.typearticleen_US
dc.contributor.departmentAGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Biyomühendislik Bölümüen_US
dc.contributor.institutionauthor
dc.identifier.doi10.4274/tybd.86158
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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