Yazar "0000-0001-6428-4207" için Biyomühendislik / Bioengineering listeleme
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3-Sulfopropyl methacrylate based cryogels as potential tissue engineering scaffolds
Durukan, Adile Yuruk; Isoglu, Ismail Alper (TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND, 2019)In this study, we developed cryogels containing 3-sulfopropyl methacrylate (SPMA) and 4-vinyl pyridine (4-VP) as a potential scaffold for tissue engineering applications. Cryogels with varying monomer ratios were synthesised ... -
HER2-Specific Peptide (LTVSPWY) and Antibody (Herceptin) Targeted Core Cross-Linked Micelles for Breast Cancer: A Comparative Study
Bayram, Nazende Nur; Ulu, Gizem Tuğçe; Abdulhadi, Nusaibah Abdulsalam; Gürdap, Seda; İşoğlu, İsmail Alper; Baran, Yusuf; İşoğlu, Sevil Dinçer (MDPI, 2023)This study aims to prepare a novel breast cancer-targeted micelle-based nanocarrier, which is stable in circulation, allowing intracellular drug release, and to investigate its cytotoxicity, apoptosis, and cytostatic ... -
Investigation of the Interaction of Adipose-Derived Mesenchymal Stem Cells with ε-Polycaprolactone and Egg White Scaffolds
Oztel, Olga N.; Yilmaz, Hilal; Isoglu, Ismail Alper; Allahverdiyev, Adil (GAZİ ÜNİVERSİTESİ, 2023)The development of three-dimensional (3D) cell culture models is becoming increasingly important due to their numerous advantages over conventional monolayer culture. This study aimed to examine the interaction of adipose ... -
On the detailed mechanical response investigation of PHBV/PCL and PHBV/PLGA electrospun mats
Bal, Burak; Tugluca, Ibrahim Burkay; Koc, Nuray; Isoglu, Ismail Alper (IOP PUBLISHING LTD, TEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND, 2019)In this study, electrospun mats of pristine poly(epsilon-caprolactone) (PCL), Poly(D, L-lactide-co-glycolide) (PLGA), poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), as well as PHBV/PCL blends and PHBV/PLGA blends in ... -
Preparation and Characterization of Viburnum Opulus Containing Electrospun Membranes as Antibacterial Wound Dressing
Yuruk, Adile; Isoglu, Sevil Dincer; Isoglu, Ismail Alper (KOREAN FIBER SOC, 2023)Herein, we fabricated polycaprolactone/gelatin electrospun membranes possessing different amounts of Viburnum Opulus extract (0, 25, 35, 50%, w/v) as an antibacterial wound dressing. We investigated chemical, morphological, ... -
Preparation of antibacterial electrospun poly(D, L-lactide-co-glycolide)/gelatin blend membranes containing Hypericum capitatum var. capitatum
Aksit, Nazende Nur; Gurdap, Seda; Isoglu, Sevil Dincer; Isoglu, Ismail Alper (TAYLOR & FRANCIS AS, KARL JOHANS GATE 5, NO-0154 OSLO, NORWAY, 2020)In this study, we fabricated poly(D, L-lactide-co-glycolide)/gelatin (PLGA/gelatin) membranes containing different amounts of Hypericum capitatum var. capitatum (HCC) extract (1, 5, 7.5, 10 wt%) by electrospinning technique. ... -
Sulfobetaine-Based Homo- and Copolymers by RAFT: Cross-Linked Micelles and Aqueous Solution Properties
Gurdap, Seda; Bayram, Nazende Nur; Isoglu, Ismail Alper; Isoglu Dincer, Sevil (AMER CHEMICAL SOC, 2022)In this study, we describe the synthesis and aqueous solution behavior of temperature-sensitive N-(3-sulfopropyl)-N-methacroyloxyethyl-N,N-dimethylammonium betaine (SBMA) homopolymers and core cross-linked micelles (CCMs) ... -
Yara Örtü Malzemesi Olarak Elektroeğrilmiş PCL/PHBV Membranların Hazırlanması ve Karakterizasyonu
İşoğlu, İsmail Alper (Bitlis Eren Üniversitesi, 2019)Bu çalışmada, yara örtü malzemesi olarak polikaprolakton (PCL), poli(3-hidroksibütirik asit-ko-3-hidroksivalerikasit) (PHBV) ve ağırlıkça farklı oranlarda (100:0, 50:50, 75:25, 0:100) PCL/PHBV karışımları, farklı ...